1,202 research outputs found
Proximity effect model of ultra-narrow NbN strips
We show that narrow superconducting strips in superconducting (S) and normal
(N) states are universally described by the model presenting them as lateral
NSN proximity systems in which the superconducting central band is sandwiched
between damaged edge-bands with suppressed superconductivity.The width of the
superconducting band was experimentally determined from the value of magnetic
field at which the band transits from the Meissner state to the static vortex
state. Systematic experimental study of 4.9 nm thick NbN strips with widths in
the interval from 50 nm to 20 m, which are all smaller than the Pearl's
length, demonstrates gradual evolution of the temperature dependence of the
critical current with the change of the strip width
Enhancement of superconductivity in NbN nanowires by negative electron-beam lithography with positive resist
We performed comparative experimental investigation of superconducting NbN
nanowires which were prepared by means of positive-and negative electron-beam
lithography with the same positive tone Poly-methyl-methacrylate (PMMA) resist.
We show that nanowires with a thickness 4.9 nm and widths less than 100 nm
demonstrate at 4.2 K higher critical temperature and higher density of critical
and retrapping currents when they are prepared by negative lithography. Also
the ratio of the experimental critical-current to the depairing critical
current is larger for nanowires prepared by negative lithography. We associate
the observed enhancement of superconducting properties with the difference in
the degree of damage that nanowire edges sustain in the lithographic process. A
whole range of advantages which is offered by the negative lithography with
positive PMMA resist ensures high potential of this technology for improving
performance metrics of superconducting nanowire singe-photon detectors
Quantitatively measuring the influence of helium in plasma-exposed tungsten
AbstractTungsten samples are exposed to 3He plasma to quantify their helium retention behavior. The retention saturates quickly with helium fluence and increases only slightly from 4.3×1019He/m2 at 773K, to 7.5×1019He/m2 at 973K. The helium content increases dramatically to 6.8×1020He/m2 when fuzz is formed on the surface of a sample exposed at 1173K, but the majority of the retained helium (5.1×1020He/m2) is found to reside below the layer of fuzz tendrils. Additional tungsten samples were exposed to either simultaneous, or sequential, D/He plasma, followed by TDS. Measurements show the majority of the D retained during simultaneous exposures is located in the near surface region of helium nano-bubbles. No deuterium was detected in any of the samples after the heating to 1273K, but 67% of the helium was released from simultaneously exposed samples, and only 23% of the helium was released from the sequentially exposed samples
Proteasome alpha-type subunit C9 is a primary target of autoantibodies in sera of patients with myositis and systemic lupus erythematosus
Autoantibodies occur in low frequencies among patients with myositis characterizing only distinct subsets of this disease. Most of these known antibodies are directed to enzymatically active complexes. The 20S proteasome represents an essential cytoplasmatic protein complex for intracellular nonlysosomal protein degradation, and is involved in major histocompatibility complex class I restricted antigen processing. In this study we investigated whether the 20S proteasome complex is an antibody target in myositis and in other autoimmune diseases. 34 sera of poly/dermatomyositis patients were assayed for antiproteasomal antibodies using enzyme-linked immunosorbent assay, immunoblot, and two-dimensional non-equilibrium pH gradient electrophoresis (NEPHGE). Sera was from patients with systemic lupus erythematosus (SLE), mixed connective tissue disease, and rheumatoid arthritis; healthy volunteers served as controls. In 62% (21/34) of the cases sera from patients with myositis and in 58% (30/52) of the cases sera from patients with SLE reacted with the 20S proteasome. These frequencies exceeded those of sera from patients with mixed connective tissue disease, rheumatoid arthritis, and healthy controls. The alpha-type subunit C9 of the 20S proteasome was determined to be the predominant target of the autoimmune sera in myositis and SLE. Lacking other frequent autoantibodies in myositis, the antiproteasome antibodies are the most common humoral immune response so far detected in this disease entity
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